Which of the following is a common side effect of Cisplatin?

Cisplatin is a chemotherapy medication commonly used to treat various types of cancer, including testicular, ovarian, bladder, and lung cancer. One of the well-known side effects associated with Cisplatin is nausea. This side effect occurs because Cisplatin can stimulate the area postrema in the brain, which is responsible for the vomiting reflex. As a result, patients undergoing treatment with this drug frequently experience significant nausea as a reaction to the medication.

While other side effects, such as dry mouth, headache, and fatigue, may occur with various medications or cancer treatments, they are not as strongly or commonly associated with Cisplatin as nausea is. Dry mouth may occur due to other processes or medications, headache could be a result of multiple factors like dehydration or stress, and fatigue is a non-specific symptom that many cancer patients experience. Nausea stands out as a highly recognized and specific side effect of Cisplatin therapy, making it the most appropriate choice regarding common side effects of this drug.