Which herbal supplement should a client receiving lorazepam avoid to prevent enhanced CNS depression?

Kava is the herbal supplement that should be avoided by a client receiving lorazepam due to its potential to enhance CNS depression. Lorazepam, as a benzodiazepine, functions as a central nervous system depressant, promoting sedation, relaxation, and anxiolysis. Kava, a plant commonly used to promote relaxation and reduce anxiety, also acts on the CNS and can exacerbate the sedative effects of medications like lorazepam. This combination could lead to increased drowsiness, impaired coordination, and potentially life-threatening respiratory depression.

In contrast, glucosamine is primarily used for joint health and does not have sedative properties that would impact the CNS. Valerian, while also a CNS depressant, is typically used for sleep disorders, but the specific concern with kava is its stronger interaction with benzodiazepines. Garlic is known for its cardiovascular benefits and does not interact with lorazepam in a way that would enhance CNS depression. Therefore, avoiding kava is crucial for maintaining safety and preventing adverse effects in clients taking lorazepam.