What is one major side effect of methotrexate that the nurse should teach the client to monitor for?

Methotrexate is a medication that is commonly used in the treatment of various conditions, including cancer and autoimmune diseases. One significant side effect associated with methotrexate is the risk of bone marrow suppression, which can lead to thrombocytopenia (low platelet count) and increase the likelihood of bleeding or bruising. Therefore, it is crucial for the nurse to educate the client about the potential for easy bruising or unusual bleeding as a result of this medication.

Monitoring for bruising is important because, while it may seem like a minor side effect, it can indicate more serious underlying issues related to effective blood cell production. If a patient starts to notice unexplained bruises, it may warrant further evaluation and possible adjustments in treatment. This proactive approach ensures that potential complications are addressed early, promoting better management of the patient’s health during methotrexate therapy.