A client receiving mirtazapine reports improvements. Which statements would indicate a therapeutic response?

Mirtazapine is an antidepressant commonly used to treat major depressive disorder. A therapeutic response to mirtazapine typically involves a decrease in the symptoms of depression. When a client states, "My depression has gotten better," it directly indicates an improvement in mood and emotional well-being, which are key signs of therapeutic effectiveness for this medication.

The other options may suggest improvements or benefits of treatment but do not specifically relate to mirtazapine's intended use for treating depression. For example, stating that one has stopped smoking could be a sign of improved overall health, but it doesn't specifically reflect the medication's impact on depressive symptoms. A decrease in blood glucose is more relevant to diabetic management rather than psychiatric treatment. Lastly, while improved sleep can be a secondary benefit of mirtazapine, it does not specifically convey a decrease in depressive symptoms, which is the primary measure of therapeutic response for this drug. Therefore, the statement about improved depression most accurately reflects the expected outcome from taking mirtazapine.